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459889 
Journal Article 
Epidemiology of atrial fibrillation: A current perspective 
Chen, LY; Shen, WK 
2007 
Yes 
Heart Rhythm
ISSN: 1547-5271
EISSN: 1556-3871 
4 
3 
S1-S6 
English 
The prevalence of atrial fibrillation (AF) increases with age. Recent population-based data indicate a trend of increasing incidence and prevalence of AF that is incompletely explained by an aging population. A recent population study estimated that the number of Americans afflicted by AF will increase from the current 2.3 million to more than 10 million by 2050. Novel risk factors-obesity and steep apnea-may partially account for the current AF epidemic. Ethnic differences in the epidemiology of AF have been suggested but not clearly elucidated by population-based studies. The heritability of AF in the general population is strongly supported by population-based data. Genetic epidemiological studies on AF can potentially yield important mechanistic insights that may ultimately lead to novel preventative and therapeutic strategies. 
atrial fibrillation; incidence; prevalence; risk factors; genetic; epidemiology; obstructive sleep-apnea; of-function mutation; c-reactive protein; risk-factors; alcohol-consumption; adrenergic activity; secular trends; heart-failure; us adults; prevalence 
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