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478664 
Journal Article 
Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome 
Hataguchi, Y; Tai, H; Nakajima, H; Kimata, H 
2005 
Yes 
European Journal of Clinical Nutrition
ISSN: 0954-3007
EISSN: 1476-5640 
59 
1093-1096 
English 
Objective: The effect of drinking deep-sea water on hair minerals was studied in patients with atopic eczema/ dermatitis syndrome (AEDS). Study of hair minerals revealed an imbalance of essential minerals and an increase in toxic minerals in AEDS patients. Design: After drinking deep-sea water (Amami no Mizu) for 6 months in AEDS patients, hair minerals ( essential minerals and toxic minerals), clinical evaluation of the skin symptoms were compared before drinking with after drinking. Subjects: After obtaining informed consent, 33 patients ( mean age 26 y, range 1 - 50 y, 13 male and 20 female subjects) with mild to moderate AEDS were enrolled. Results: After drinking deep-sea water, the levels of the essential mineral, potassium ( K), were significantly decreased, while the levels of selenium ( Se) increased. On the other hand, drinking deep-sea water significantly decreased the levels of the toxic minerals, mercury and lead. Moreover, after drinking deep-sea water, the skin symptoms were improved in 27 out of 33 patients. Conclusion: These results indicate that the mineral abnormalities/imbalance may be involved in the pathogenesis of AEDS, and that drinking deep-sea water may be useful in the treatment of AEDS. 
atopic eczema/dermatitis syndrome; deep sea water; hair minerals; dermatitis-like symptoms; magnesium; epidermis; eczema; hair; zinc; skin 
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