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4956945 
Journal Article 
Voltammetric Behavior of Leucovorin on Mercury Meniscus Modified Silver Solid Amalgam Electrode 
Bandzuchova, L; Selesovska, R 
2011 
20-24 
WOS:000304395000004 
The voltammetric behavior of leucovorin (folinic acid, LV), as an important metabolite of folic acid, has been investigated in this paper. Mercury meniscus modified silver solid amalgam electrode (m-AgSAE) as a working electrode in connection with differential pulse voltammetry (DPV) was applied for monitoring of electrochemical reduction of leucovorin. The limit of detection was found as 1.84x10(-8) M (t(acc) = 60s). Proposed method was successfully applied for LV determination in a drug which is used as an antidote during methotrexate treatment. 
leucovorin; mercury meniscus modified silver solid amalgam electrode; hanging mercury drop electrode; differential pulse voltammetry 
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