US EPA

4968663 

Journal Article 

Fate of a hydrocarbon pollution indicator in fish: absorption, deposition and depuration of squalane in Salmo gairdneri R 

Cravedi, JP; Tulliez, J 

1986 

1 

Environmental Pollution Series A: Ecological and Biological
ISSN: 0143-1471 

42 

3 

247-259 

English 

10.1016/0143-1471(86)90035-8 

WOS:A1986E371700006 

http://linkinghub.elsevier.com/retrieve/pii/0143147186900358
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Absorption, distribution, and release of squalane were studied in rainbow trout fed a diet containing 0.05% of this alkane. Estimated squalane absorption was about 40% of the dose. After three months of exposure, the residues in the whole body reached a steady equilibrium value of about 16- 18 micrograms/g. The most pronounced deposition occurred in the liver (1671 micrograms/g after 10 months), while the concentration of squalane in the adipose tissue was below 2 micrograms/g. During the depuration period, half of the contaminated trout were fed a squalane-free diet, while the others were starved. After two months, the body burden amounted to 65% and 80% of the alkane previously accumulated in starved and fed trout, respectively. In the starved group, 43% of the squalane initially stored in the liver was lost, whereas the loss in the fed fish liver was 52%. These results were compared with existing data on other alkanes. (Author 's abstract) 

Bioindicators; Water pollution; Fate of pollutants; Fish; Absorption; Deposition; Depuration; Squalane; Trout; Organic compounds; Tissue analysis; Feces; Toxicity; Fish physiology; Animal physiology; Biotransformation; Metabolism; Population exposure