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5018062 
Journal Article 
Positive Allosteric Control of Guests Encapsulation by Metal Binding to Covalent Porphyrin Cages 
Djemili, R; Kocher, L; Durot, S; Peuronen, A; Rissanen, K; Heitz, V 
2019 
Yes 
Chemistry: A European Journal
ISSN: 0947-6539
EISSN: 1521-3765 
25 
1481-1487 
English 
The allosteric control of the receptor properties of two flexible covalent cages is reported. These receptors consist of two zinc(II) porphyrins connected by four linkers of two different sizes, each incorporating two 1,2,3-triazolyl ligands. Silver(I) ions act as effectors, responsible for an on/off encapsulation mechanism of neutral guest molecules. Binding silver(I) ions to the triazoles opens the cages and triggers the coordination of pyrazine or the encapsulation of N,N'-dibutyl-1,4,5,8-naphthalene diimide. The X-ray structure of the silver(I)-complexed receptor with short connectors is reported, revealing the hollow structure with a cavity well-defined by two eclipsed porphyrins. Rather unexpectedly, the crystallographic structure of this receptor with pyrazine as a guest molecule showed that the cavity is occupied by two pyrazines, each binding to the zinc(II) porphyrin in a monotopic fashion. 
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