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610310 
Journal Article 
IMPACT OF CHLOROPRENE AND ITS DERIVATIVES ON FERMENTAL SYSTEMS IN WORKERS ENGAGED IN THE PRODUCTION OF SYNTHETIC RUBBER 
Khlgatyan, DS; Nersesova, LS; Gazaryants, MG; Mkrtchyan, ZS; Meliksetyan, GO; Pogosyan, LG; Kostandyan, SR; Akopyan, ZI 
2009 
0 
Toksikologicheskii Vestnik
ISSN: 0869-7922 
2 
9-13 
Labor conditions of workers engaged in chloroprene rubber production are characterized by exposure to a complex of chemical compounds among which the leading part is played by chloroprene and products Of its interaction with hydroxyl radicals and atmospheric ozone. It was shown with certainty that the activity of creatine kinase and purine nucleoside phosphorylase decreases 2-fold as compared to the control in blood serum Of workers engaged in chloroprene synthesis. Changes in enzymes activity are not related to gender, age or length of service. Activity of serumal alanine aminotransferase (ALT) and aspartate aminotransferase(AST) did not revealed any changes in those workers. 
IRIS
• Chloroprene
     Not Cited