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Citation
Tags
HERO ID
63181
Reference Type
Journal Article
Subtype
Abstract
Title
The metabolism of [14C]hexachloroethane
Author(s)
Jondorf, WR; Parke, DV; Williams, RT
Year
1957
Is Peer Reviewed?
Yes
Journal
Biochemical Journal
ISSN:
0264-6021
EISSN:
1470-8728
Report Number
NIOSH/00060207
Volume
65
Page Numbers
14P-15P
Abstract
The metabolism of carbon-14(C-14) labeled hexachloroethane(C2-C116) (67721) was studied in experimental rabbits. Three days after feeding the animals 0.5 g/kg C2-C116 containing C-14 in both carbon (7440440) atoms, 5 percent of the radioactivity appeared in the urine and 14-24 percent in the expired air. Analysis of labeled metabolites in the urine and the expired air by chromatography and isotope-dilution techniques yielded a number of chlorinated and other compounds, including the highly toxic urinary metabolite monochloroacetic-acid (79118).
Tags
•
Hexachloroethane (HCE) (Final, 2011)
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