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1041951 
Journal Article 
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora 
Niño, J; Hernández, JA; Correa, YM; Mosquera, OM 
2006 
1 
Memórias do Instituto Oswaldo Cruz
ISSN: 0074-0276
EISSN: 1678-8060 
101 
7 
783-785 
English 
17160288 
WOS:000242284100013 
The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family. 
acetylcholinesterase (AChE) inhibitors; Asteraceae; Euphorbiaceae; Melastomatacea; Rubiaceae; Solanaceae 
IRIS
• Methanol (Non-Cancer)
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