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HERO ID
1104556
Reference Type
Journal Article
Title
Commentary: update on animal models for NTP studies
Author(s)
King-Herbert, AP; Sills, RC; Bucher, JR
Year
2010
Is Peer Reviewed?
1
Journal
Toxicologic Pathology
ISSN:
0192-6233
EISSN:
1533-1601
Volume
38
Issue
1
Page Numbers
180-181
Language
English
PMID
20019353
DOI
10.1177/0192623309356450
Abstract
Based on recommendations of participants at the National Toxicology Program (NTP) workshop "Animal Models for the NTP Cancer Bioassay: Strains and Stocks-Should We Switch?" some modifications to the NTP rodent cancer bioassay were made. The B6C3F1 remains the mouse model used in the cancer bioassay. The use of multiple strains of mice will be explored through a new branch within the NTP, the Host Susceptibility Branch. Several rat models were evaluated; the Harlan Sprague Dawley rat is currently being used in the NTP studies.
Tags
IRIS
•
Methanol (Non-Cancer)
Ramazzini
•
Ramazzini Institute
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