Identification of oil-soluble coal tar dyes in cosmetics using reversed-phase TLC/scanning densitometry | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1157605

Reference Type

Journal Article

Title

Identification of oil-soluble coal tar dyes in cosmetics using reversed-phase TLC/scanning densitometry

Author(s)

Ohno, T; Mikami, E; Matsumoto, H

Year

2003

Is Peer Reviewed?

Yes

Journal

Journal of Health Science
ISSN: 1344-9702
EISSN: 1347-5207

Publisher

PHARMACEUTICAL SOC JAPAN

Location

TOKYO

Volume

Issue

Page Numbers

401-404

Language

English

DOI

10.1248/jhs.49.401

Web of Science Id

WOS:000185784900013

Abstract

A simple and rapid analytical method of oil-soluble coal tar dyes in cosmetics was established using reversed-phase TLC/scanning densitometry. Eleven kinds of oil-soluble coal tar dyes were able to be separated completely on reversed-phase TLC plates by the complementary use of 2 solvent systems. The solvent systems were A; n-hexane/2-butanone solution (5:1, v/v), solvent system B; acetonitrile/methanol solution (5:1, v/v). Then we measured visible absorption spectra of spots developed on the reversed-phase TLC plates by scanning densitometer to identify these coal tar dyes. The proposed method was successfully applied to the identification of oil-soluble coal tar dyes in commercial cosmetics.

Keywords

oil-soluble coal tar dye; reversed-phase TLC; scanning densitometry; cosmetic