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Citation
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HERO ID
1247293
Reference Type
Data & Software
Subtype
Database
Title
Benzo(a)pyrene [CASRN 50-32-8]
Author(s)
Hazardous Substances Data Bank :: HSDB
Year
2012
Publisher
National Library of Medicine
Location
Bethesda, MD
Language
English
URL
http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB
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Relationship(s)
uses data from
3036233
Hazardous substances data bank
Abstract
CLASSIFICATION: B2; probable human carcinogen. BASIS FOR CLASSIFICATION: Human data specifically linking benzo(a)pyrene (BAP) to a carcinogenic effect are lacking. There are, however, multiple animal studies in many species demonstrating BAP to be carcinogenic following administration by numerous routes. BAP has produced positive results in numerous genotoxicity assays. NOTE: At the June, 1992 CRAVE Work Group meeting, a revised risk estimate for benzo(a)pyrene was verified. ... The Carcinogenicity Background Document provides details on the rationale and methods used to derive the carcinogenicity values found in IRIS. ... HUMAN CARCINOGENICITY DATA: Inadequate. ANIMAL CARCINOGENICITY DATA: Sufficient. /Based on former classification system/
[U.S. Environmental Protection Agency's Integrated Risk Information System (IRIS) on Benzo(a)pyrene (BaP) (50-32-8) Available from, as of March 15, 2000. http://www.epa.gov/iris/ **PEER REVIEWED**
Tags
IRIS
•
Benzo(a)pyrene (BaP)
Considered
Cited
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