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1311693 
Journal Article 
Analysis Toward Innovative Herbal Antibacterial & Antifungal Drugs 
Dhankhar, S; Dhankhar, S; Kumar, M; Ruhil, S; Balhara, M; Chhillar, AK 
2012 
1 
Recent Patents on Anti-Infective Drug Discovery
ISSN: 1574-891X 
Bentham Science Publishers Ltd., P.O. Box 640310 San Francisco CA 94164-0310 
7 
3 
242-248 
English 
23072646 
The antimicrobial activities of four medicinal plants Argemona mexicana, Achyranthes aspera, Catharanthus roseus, and Syzygium cumini were evaluated against Escherichia coli, Vibrio cholerae, Klebsiella pneumoniae, Proteus vulgaris, Bacillus subtilis, Salmonella typhi and three Aspergillus species. Extracts from Achyranthes aspera and Catharanthus roseus showed the highest antimicrobial potential (MIC 0.375-0.750 mg/ml) while extract from Argemona mexicana and Syzygium cumini, showed less activity. In disc diffusion assay, only eight out of twenty extracts showed antimicrobial activity at a concentration of 25.0 µg/ disc. The GCMS investigation reveals the existence of 2-bornanone; 1, 2-benzenedicarboxylic acid, bis (2-methylpropyl) ester; hexadecanoic acid, methyl ester and hexatriacontane in water extract fraction of C. roseus. The present research article provides a review of some medicinal plants incorporating antimicrobial drugs, together with recent advances in emerging therapeutics in clinical development and related patents for exploitation of herbal medicine. 
Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; Medicinal plants; Patents; Antimicrobial activity; Bacillus subtilis; Herbal medicines; Vibrio cholerae; Escherichia coli; Salmonella typhi; Antimicrobial agents; Catharanthus roseus; Palmitic acid; Drug development; Achyranthes aspera; Syzygium cumini; Aspergillus; Reviews; Minimum inhibitory concentration; Diffusion; Proteus vulgaris; Klebsiella pneumoniae; K 03420:Plant Diseases; A 01340:Antibiotics & Antimicrobials; J 02340:Antibiotics & Antimicrobials 
• Diisobutyl Phthalate (DIBP) Final
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