OBJECTIVE: To study the chemical constituents in the roots of Pueraria lobata.
METHOD: Various chromatographic methods were employed to separate of chemical constituents and the spectroscopic methods were used to elucidate the structure.
RESULT: Twenty-two compounds were isolated and characterized as beta-sitosterol palmitate (1), beta-sitosterol (2), lupeol (3), lupeone (4) , puerarol (5), diisobutyl phthalate (6), bis(2-ethylhexyl) phthalate (7), sophoracoumestan A (8), coumestrol (9), allantion (10), dadzein (11), formononetin (12), 3'-methoxy daidzein (13), ononin (14), 3'-hydroxy dadzein (15), genistin (16), dadzin (17), 8-methoxy ononin (18), sissotorin (19), (-)-puerol B 2-O-glucopyranoside (20), (6S,9R)-roseoside (21) and sucrose (22), respectively.
CONCLUSION: Compounds 1, 5-8, 15, 18, 21 and 22 were isolated from P. lobata for the first time, and componds 1, 5-7, 15, 18, 21 and 22 were isolated from the genus Pueraria for the first time.
Chemical constituents; Isoflavonoids; Pueraria lobata; Steroids; 3' hydroxy dadzein; 3' methoxy daidzein; 8 methoxy ononin; allantion; coumestrol; dadzein; dadzin; diisobutylphthalate; formononetin; genistin; lupeol; lupeone; ononin; phthalic acid bis(2 ethylhexyl) ester; Pueraria extract; puerarol; puerol beta 2 o glucopyranoside; roseoside; sissotorin; sitosterol; sitosterol palmitate; sophoracoumestan; sucrose; unclassified drug; article; clinical evaluation; drug isolation; plant root; Pueraria; Pueraria lobata; spectroscopy; Plant Extracts; Plant Roots; Pueraria
