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Citation
Tags
HERO ID
1367502
Reference Type
Journal Article
Title
Efficacy of directional coronary atherectomy in cases unsuitable for percutaneous transluminal coronary angioplasty (PTCA) and after unsuccessful PTCA
Author(s)
Höfling, B; Gonschior, P; Simpson, L; Bauriedel, G; Nerlich, A
Year
1992
Is Peer Reviewed?
Yes
Journal
American Heart Journal
ISSN:
0002-8703
EISSN:
1097-6744
Volume
124
Issue
2
Page Numbers
341-348
Language
English
PMID
1636578
Abstract
Directional coronary atherectomy (DCA) was used in 10 female and 50 male patients with an average age of 58 years. They were categorized into three different groups depending on the indications for atherectomy. Group 1 included all patients who had atherectomy as their primary intervention (n = 20) because they were assumed to be unsuitable for percutaneous transluminal coronary angioplasty (PTCA). Group 2 consisted of patients in whom DCA was used after failed balloon dilatation with unsuccessful but uneventful treatment (n = 17). Group 3 (n = 23) included patients in whom DCA was performed as a "rescue" or "bailout" procedure after unsuccessful PTCA resulting in critical ischemia (ECG changes, chest pain, hypotension, and shock). The target lesions were located in the left main artery in two, left anterior descending artery in 43, right coronary artery in 15, and aortocoronary venous bypass in five. The mean length of the lesions was 8 mm (2 to 25 mm). The overall success rate for 65 lesions was 92%. The mean stenosis was reduced from 87 +/- 12% to 19 +/- 17% in patients with primary success. Presently available follow-up angiograms (30) showed six restenoses. Major complications occurred in seven patients (myocardial infarction in two and coronary artery bypass graft surgery within 24 hours in five); there were no deaths. Our results show that DCA is a safe and effective technique that can extend the use of percutaneous procedures and provide a promising nonsurgical option in cases of unsuccessful PTCA.
Tags
IRIS
•
Arsenic (Inorganic)
1. Literature
PubMed
4. Adverse Outcome Pathways/Networks Screening
Excluded/Not relevant
Electronic discard
•
Arsenic MOA
2. Electronic Discard
1. MOA Literature Screening
MOA Cluster
•
Inorganic Arsenic (7440-38-2) [Final 2025]
1. Initial Lit Search
PubMed
4. Considered through Oct 2015
6. Cluster Filter through Oct 2015
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