US EPA

1457070 

Journal Article 

Effects of dietary sodium butyrate supplementation on the intestinal morphological structure, absorptive function and gut flora in chickens 

Hu, Z; Guo, Y 

2007 

Yes 

Animal Feed Science and Technology
ISSN: 0377-8401 

132 

3-4 

240-249 

English 

10.1016/j.anifeedsci.2006.03.017 

WOS:000243579200006 

A study was carried out to investigate the effects of dietary sodium butyrate (SB) on the intestine and growth performance in chickens. Three hundred and thirty six day-old AA broiler chicks were allocated at random into four groups with six replicates each. Four groups were fed with basal diet (control) or diets supplemented with SB at the level of 500, 1000, 2000mg/kg. Body weight gain increased linearly during the period from 0 to 21 days as the dietary supplementation of SB increased (P < 0.05). Dietary supplementation of SB influenced feed conversion ratio(FCR) in a positive quadratic fashion during the period from 0 to 42 days (P < 0.05). Dietary SB did not influence the absorptive function of jejunum (P > 0.05). The concentrations of DNA, RNA, and protein in duodenal mucosa showed negative quadratic responses to the increase of dietary SB supplementation level (P < 0.05). The ratio of villus height to crypt depth increased linearly with the increase of dietary SB supplementation (P < 0.01). The Lactobacillus count decreased linearly with the increase of dietary SB supplementation (P < 0.01). (c) 2006 Elsevier B.V. All rights reserved. 

butyrate; chicken; intestinal morphological structure; absorptive function; digestive microflora