A simple deprotection of triflate esters of phenol derivatives | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1491318

Reference Type

Journal Article

Title

A simple deprotection of triflate esters of phenol derivatives

Author(s)

Ohgiya, T; Nishiyama, S

Year

2004

Is Peer Reviewed?

Journal

Tetrahedron Letters
ISSN: 0040-4039
EISSN: 1873-3581

Volume

Issue

Page Numbers

6317-6320

DOI

10.1016/j.tetlet.2004.06.104

Web of Science Id

WOS:000223112100022

URL

http://://WOS:000223112100022
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Abstract

Efficient conversion of aryl triflates into the
corresponding phenols has been accomplished with Et4NOH. In contrast to other cleavage reactions,
such functional groups as nitro, ketone, halogen, amide and sulfonamide groups were intact under
the reaction conditions. This mild removal of the trifluoromethanesulfonyl group would serve a
new protecting group of phenols. (C) 2004 Elsevier Ltd. All rights reserved.

Keywords

protecting group; aryl sulfonates; trifluoromethanesulfonyl group; Et4NOH