Genome-wide association studies for common diseases and complex traits
Hirschhorn, JN; Daly, MJ
HERO ID
2328033
Reference Type
Journal Article
Subtype
Review
Year
2005
Language
English
PMID
| HERO ID | 2328033 |
|---|---|
| Material Type | Review |
| In Press | No |
| Year | 2005 |
| Title | Genome-wide association studies for common diseases and complex traits |
| Authors | Hirschhorn, JN; Daly, MJ |
| Journal | Nature Reviews. Genetics |
| Volume | 6 |
| Issue | 2 |
| Page Numbers | 95-108 |
| Abstract | Genetic factors strongly affect susceptibility to common diseases and also influence disease-related quantitative traits. Identifying the relevant genes has been difficult, in part because each causal gene only makes a small contribution to overall heritability. Genetic association studies offer a potentially powerful approach for mapping causal genes with modest effects, but are limited because only a small number of genes can be studied at a time. Genome-wide association studies will soon become possible, and could open new frontiers in our understanding and treatment of disease. However, the execution and analysis of such studies will require great care. |
| Doi | 10.1038/nrg1521 |
| Pmid | 15716906 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |