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HERO ID
3224051
Reference Type
Journal Article
Title
Air Pollution and the Risk of Birth Defects in Anqing City, China
Author(s)
Yao, C; Chen, Y; Zhu, X; Liu, Y; Zhang, J; Hou, L; Xu, Y; Zhang, C; Cao, J
Year
2016
Is Peer Reviewed?
Yes
Journal
Journal of Occupational and Environmental Medicine
ISSN:
1076-2752
EISSN:
1536-5948
Volume
58
Issue
4
Page Numbers
e124-e127
Language
English
PMID
27058489
DOI
10.1097/JOM.0000000000000676
Web of Science Id
WOS:000374891600003
URL
https://journals.lww.com/00043764-201604000-00020
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Abstract
OBJECTIVE:
This study aimed to explore evidence for the influence of air pollution on the risk of birth defects in China and contribute to establish prevention strategies.
METHODS:
We conducted a retrospective cohort study in Anqing city, Eastern China, from 2010 to 2012. Binary logistic regression models were used to estimate odds ratios (ORs) per 10 μg/m3 change for SO2, NO2, and PM10.
RESULTS:
For continuous exposure to SO2 (10 μg/m increase), the adjusted OR for birth defects is 1.20 [95% confidence interval (95% CI) 1.09 to 1.29] in the preconception. A 10 μg/m increase in SO2 (adjusted OR 1.26, 95% CI 1.15 to 1.36) during the second trimester is strongly associated with birth defects. No associations have been observed for NO2 and PM10.
CONCLUSION:
The results suggested that exposure to ambient SO2 during pregnancy may increase the risk of birth defects.
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