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4944809 
Journal Article 
Tumor-promoting activity of n-alkanes and 1-alkanols 
Sice, J 
1966 
No 
Toxicology and Applied Pharmacology
ISSN: 0041-008X
EISSN: 1096-0333 
9 
1 
70-74 
English 
Pure n-alkanes and 1-alkanols promoted papilloma growth in the skin of Swiss mice which had been treated with a noncarcinogenic dose of dimethylbenzanthracene. Decanol, dodecane, and tetradecane were the most potent; hexanol, hexane, and octane were inactive. One-fourth of the papillomas became squamous cell carcinomas. A difference of two carbon atoms separated equipotent alkanes and alkanols. The tumor-promoting effect of these substances was not identical with that of a croton extract studied under similar conditions. 
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