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538458 
Journal Article 
Effects of lead and particulate montmorillonite on growth performance, hormone and organ weight in pigs 
Yu, DY; Xu, ZR; Yang, XG 
2005 
Yes 
Asian - Australasian Journal of Animal Sciences
ISSN: 1011-2367
EISSN: 1976-5517 
18 
12 
1775-1779 
English 
WOS:000232238700017 
Seventy-two crossbred gilts of approximately 33 kg initial weight were used in this study. The gilts were randomly assigned into three groups. The three dietary treatments were basal diet only (control group), basal diet+10 mg/kg lead, and basal diet+10-mg/kg lead+.0.5%. particulate montmonlionite (PM). The results showed that the :addition of lead to the diet decreased significantly the body weight and feed efficiency, but PM could restore body weight and feed efficiency of gilts compared to the Pb exposure group. There were no significant differences in weights of ovaries and uteri with addition of either lead or PM to the diet. Supplementing the lead in the diet of gilts also significantly increased the concentration of lead in blood, decreased circulating lutenizing hormone (LH) and estradiol (E-2) levels in serum, the addition of PM to the diet effectively adsorbed and lowered lead concentration in the blood. These data suggested that lead disrupts the signals between the hypothalamus and pituitary gland in gilts, and possibly suppressed the secretion of relative growth hormone and sex hormone. On the other hand, PM may ameliorate Pb toxicity in pigs. 
particulate montmorillonite; lead; growth; hormone; pigs; pubertal development; pb exposure; blood lead; rat; toxicity; cadmium; adsorption; pituitary; responsiveness; lactation 
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