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619588 
Journal Article 
Antioxidant and anti-quorum sensing activities of green pod of Acacia nilotica L 
Singh, BN; Singh, BR; Singh, RL; Prakash, D; Sarma, BK; Singh, HB 
2009 
Yes 
Food and Chemical Toxicology
ISSN: 0278-6915
EISSN: 1873-6351 
47 
778-786 
English 
Abstract: The antioxidant and anti-quorum sensing activities of eight extracts were studied in green pods of Acacia nilotica. The specific phenolic compositions and their quantifications were performed by HPLC and MS/MS, which showed that the HEF (pH 4) was higher in gallic acid, ellagic acid, epicatechin, rutin, and GTs. In order to find antioxidant potential of various extracts, their activities were studied for TPC, AOA, FRSA, RP, inhibition of LPO, FIC activity, HO and scavenging activities. Among them HEF (pH 4) has shown potent antioxidant activity. HEF (pH 4) was also found effective in protecting plasmid DNA and HAS protein oxidation induced by HO . Pre-treatment of HEF (pH 4) at 75 and 150mg/kg body weight for 6 days caused a significant increase in the levels of CAT and SOD and decrease in the level of MDA content in liver, lungs, kidneys and blood when compared to CCl4-intoxicated rats. Eventually, the extracts were also screened for anti-QS activity. Of these extracts two showed QS inhibition: HEF (pH 4) and HCE. The results obtained strongly indicate that green pod of A. nilotica are important source of natural antioxidants. [Copyright 2009 Elsevier] Copyright of Food & Chemical Toxicology is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts) 
1,1-diphenyl-2-picrylhydrazyl ( DPPH ); 2,4-dinitrophenylhydrazine ( DNPH ); anti-radical power ( ARP ); antioxidant activity ( AOA ); ascorbic acid equivalent ( ASE ); butylated hydroxytoluene ( BHT ); butylated hyroxyanisole ( BHA ); carbon tetrachloride ( CCl4 ); catalase ( CAT ); ferrous ion chelation ( FIC ); free radical scavenging activity ( FRSA ); human serum albumin ( HSA ); hydrogen peroxide ( H2O2 ); hydroxyl radical(s) ( HO ); lipid peroxidation ( LPO ); malondialdehyde ( MDA ); nicotinamide adenine dinucleotide ( NADH ); nitro blue tetrazolium ( NBT ); phenazine methosulphate ( PMS ); protein carbonyl ( PCO ); reducing power ( RP ); sodium dodecyl sulphate ( SDS ); superoxide dismutase ( SOD ); superoxide radical(s) ( ); thiobarbituric acid ( TBA ); total phenolic content ( TPC ); trichloroacetic acid ( TCA ) 
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