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75175 
Journal Article 
Trichloroethylene exposure and trichloroethylene metabolites in urine and blood 
Muller, G; Spassovski, M; Henschler, D 
1972 
Yes 
Archives of Toxicology
ISSN: 0340-5761
EISSN: 1432-0738 
29 
4 
335-340 
English 
4647062 
After trichloroethylene (Tri) inhalation the metabolite trichloroethanol (TCE) is excreted rapidly in the urine, while trichloroacetic acid (TCA) accumulates in the organism due to a high plasma protein binding rate. After exposure of 5 volunteers to 50 ppm Tri for 6 h, 50 mgrg/ml TCA is found in the plasma at the end of the 5th exposure day, the amount of TCE present in the blood amounting to not more than 2.3 mgrg/ml. Instead of the previously used control of TCE + TCA in the urine, it is suggested to determine the metabolites in the blood by means of a gas Chromatographic micro technique which provides a reliable criterion of the preceding Tri exposure. 
• Trichloroacetic acid (TCA) (Final, 2011)
• Trichloroethylene (TCE) (Final, 2011)
     All References
     Toxicokinetics
     PBPK Modeling
OPPT REs
• OPPT_Trichloroethylene (TCE)_F. Human Health
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          ADME