US EPA

1357084 

Technical Report 

Arsenic and its inorganic compounds 

Anonymous 

2001 

Joint Group of Experts on the Scientific Aspects of Marine Pollution (GESAMP) 

RISKLINE/2002040032 

Documentation of the threshold limit values and biological exposure indices
Vol 

2001 

eng 

is also published as 667873 Arsenic and its inorganic compounds

A TLV-TWA of 0.01 mg/m3, measured as arsenic (As), is recommended for occupational exposure to elemental arsenic and its inorganic compounds, excluding arsine (see the TLV Documentation for Arsine). This value is intended to minimize the potential for adverse effects on the skin, liver, peripheral vasculature, upper respiratory tract, and lungs, including cancer. The singular important and conclusive evidence that arsenic is a human carcinogen warrants its designation as an A1, Confirmed Human Carcinogen. Accordingly, worker exposure by all routes should be carefully controlled to levels as low as possible below the TLV. Sufficient data were not available to recommend Skin or SEN notations or a TLV-STEL. Arsenic is a substance for which Biological Exposure Indices (BEIs) have been recommended(see BEI Documentation for Arsenic, Elemental and Soluble Inorganic Compounds). 

ANIMAL; carcinogenicity; carcinogens; genetic toxicity; reproductive and developmental tests; teratogens; respiratory system; HUMAN; epidemiological study; case report; human exposure; chronic effect; carcinogenic effect; genetic effect; toxicokinetics; skin; liver; cardiovascular system; respiratory system; metallurgy; pesticides; glass industry; tobacco smoke