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1459848 
Journal Article 
Antidiabetic activity of phenolic compounds from Pecan bark in streptozotocin-induced diabetic rats 
Abdallah, HM; Salama, MM; Abd-Elrahman, EH; El-Maraghy, SA 
2011 
0 
Phytochemistry Letters
ISSN: 1874-3900
EISSN: 1876-7486 
4 
3 
337-341 
English 
WOS:000296534500029 
The n-butanol fraction (BF) of bark of Pecan tree, Carya illinoinensis (Wangenh) K. Koch (Juglandaceae) afforded two new flavonol methyl ether: caryatin-3' sulfate (6) and caryatin-3' methyl ether-7-O-beta-D-glucoside (7) while five known phenolics (1-5) were isolated from its ethyl acetate fraction (EAF). The structures of isolated compounds were established based on 1D and 2D NMR spectroscopy. The isolated compounds were investigated for their hypoglycaemic, antioxidant as well as the aldose reductase (AR) inhibitory effect in lenses of streptozocin diabetic rats. All the isolated compounds showed significant hypoglycaemic and antioxidant activities, except 5 and 6. A marked AR-inhibitory effect was identified for compounds 2, 3 and 7. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. 
Pecan bark; Aldose reductase; Methoxy flavonoids; Sulphated flavonoids; Antidiabetic 
IRIS
• n-Butanol
     Database searches
          WOS
     Source – January 2013 (private)
          WOS - 1/2013
          Merged reference set - 1/2013
     Excluded (not pertinent)
          Not chemical specific