US EPA

1482764 

Journal Article 

High-Performance Liquid Chromatography Of Organometallic Compounds 

Ermoshkin, AE; Makarenko, NP; Sakodynskii, KI 

1984 

1 

Journal of Chromatography
ISSN: 0021-9673 

ELSEVIER SCIENCE BV 

AMSTERDAM 

NIOSH/00142633 

290 

C 

377-391 

English 

10.1016/S0021-9673(01)93591-5 

WOS:A1984ST69800036 

A method for separating organometallic compounds was developed. High performance liquid chromatography (HPLC) columns were slurry packed. n-Hexane containing diethyl-ether was the eluent at a flow rate of 1 to 2 milliliters per minute. The 1 microliter samples were diluted in n-hexane. The input pressure was 40 atmospheres and measurements were made at 22 degrees-c. Retention time of silicon (7440213) containing phenols increased when the hindrance of the phenol hydroxy group decreased. Germanium (7440564) containing phenols was retained more strongly than silicon containing phenols. A decrease in retention was observed when bromine (7726956) was introduced into silicon containing phenols. With substituted naphthalenes there was a correlation between an increase in electron density on the aromatic system and an increase in retention time. Triphenyl derivatives of bismuth (7440699) were retained more strongly than triphenyl derivatives of phosphorus (7723140). Pentaphenyl derivatives of phosphorus and antimony (7440360) were retained less strongly than their triphenyl counterparts. Ferrocenyl and cymanthrenyl derivatives of antimony were retained more strongly than the corresponding derivatives of bismuth. The authors conclude that HPLC may be used to elucidate the chemical characteristics of organometallic compounds. 

DCN-130178; Quantitative analysis; Research; Analytical chemistry; Analytical methods; Laboratory techniques; Trace analysis; Chromatographic analysis; Organophosphorous compounds; Organic compounds; Metallic compounds; Chemical composition