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1483142 
Technical Report 
IARC (International Agency for Research on Cancer) Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, No. 8. Some aromatic azo compounds 
Ward, E 
1975 
HEEP/76/08930 
INT AGENCY RES CANCER 
INT AGENCY RES CANCER 
HEEP COPYRIGHT: BIOL ABS. Over 30 azo compounds are evaluated for possible carcinogenic activity. The evaluation process is described in the opening section. Individual chapters are devoted to each of the following azo compounds: Amaranth (3-hydroxy-4-((4-sulfo-1-naphthalenyl)azo)-2,7-naphthalenedisulfonic acid, trisodium salt); Para-aminoazobenzene; Ortho-aminoazotoluene; Azobenzene; Carmoisine 4-hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-1-naphthalenesulfonic acid, disodium salt); Chrysoidine (4-(phenylazo)-1,3-benzenediamine, monohydrochloride); Disperse yellow 3 (N(4-((2-hydroxy-5-methylphenyl)azo)phenyl)-acetamide); Citrus red No. 2 (1-((2,5-dimethoxyphenyl)azo)-2-naphthalenol); d and C red No. 9 (5-chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methylbenzenesulfonic acid, barium salt); Diacetylaminoazotoluene (N-acetyl-N-(2-methyl-4-((2-methylphenyl)azo)-phenyl)-acetamide; 2,6-diamino-3-(phenylazo)pyridine (hydrochloride); Para-dimethylaminoazobenzene; Para-dimethylaminobenzenodiazo sodium sulfonate; Evans Blue (6,6'-((3,3'-dimethyl(1,1-biphenyl)-4,4'-diyl)bis (azo))-bis(4-amino-5-hydroxy)-1,3-naphthalenedisulfonic acid, tetrasodium salt); 4-Hydroxyazobenzene; Methyl red (2-((4-dimethylamino)phenylazo)benzoic acid); Oil orange SS (1-((2-methylphenylazo)-2-maphthalenol); Orange I (4-((4-hydroxy-1-maphthalenyl)azo)benzenesulfonic acid, monosodium salt); Orange G (7-hydroxy-8-(phenylazo)-1,3-naphthalenedisulfonic acid, disodium salt; Ponceau MX (4-((2,4-dimethylphenyl)azo)-3-hydroxy-2,7-naphthalenedisulfonic acid, disodium salt; Ponceau 3R (3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-2,7-naphthalenedisulfonic acid, disodium salt); Ponceau SX (3-((2,4-dimethyl-5-sulfophenyl)azo)-4-hydroxy-1-naphthalenesulfonic acid, disodium salt); Scarlet red (1-((2-methyl-4-((2-methlphenyl)azo)phenyl)azo)-2-naphthalenol); Sudan I (1-(phenylazo)-2-naphthalenol); Sudan II (1-((2,4-dimethylphenyl)azo)-2-naphthalenol); Sudan III (1-((4-(phenylazo)phenyl)azo)-2-naphthalenol); Sudan Brown RR (4-(1-naphthylazo)-1,3-phenylenediamine; Sudan Red 7B (N-ethyl-1-((4-(phenylazo)phenyl)azo)-2-naphthaleneamine); Sunset Yellow FCF (6-hydrox-5-((4-sulfophenyl)azo)-2-naphthalene-sulfonic acid, disodium salt); Trypan blue (3,3'-((3,3-dimethyl(1,1'-biphenyl)4,4'diyl)bis (azo))bis(5-amino-4-hydroxy)-2,7-naphthalenedisulfonic acid, tetrasodium salt); Yellow AB (1-(phenylazo)-2-naphthalenamine) and Yellow OB (1-(2-methylphenyl)azo-2-naphthalenamine). The chemical and physical properties, production, use, occurrence and carcinogenicity in animals and man are examined for each azo compound.