Extraction spectrophotometric determination of tamoxifen citrate using Naphthalene Blue 12BR or Alizarine Red-S | Health & Environmental Research Online (HERO)

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HERO ID

1487544

Reference Type

Journal Article

Title

Extraction spectrophotometric determination of tamoxifen citrate using Naphthalene Blue 12BR or Alizarine Red-S

Author(s)

Sastry, CS; Lingeswara Rao, JS

Year

1995

Is Peer Reviewed?

Yes

Journal

Indian Journal of Pharmaceutical Sciences
ISSN: 0250-474X
EISSN: 1998-3743

Report Number

IPA/96/1094474

Volume

Pharm

Issue

REF

Page Numbers

133-135

Language

English

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029002197&partnerID=40&md5=08d663439445fdd8fece45be26488ef9
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Abstract

Simple, rapid and sensitive spectrophotometric methods have been described for the determination of Tamoxifen Citrate, based on the formation of chloroformsoluble ion-association complex between Tamoxifen and the dye (Naphthalene Blue 12BR or Alizarin Red-S) in acidic medium. The coloured species exhibit maximum absorbance at 620 and 440 nm respectively.

Keywords

Tamoxifen citrate; spectrometry; Antineoplastic agents; tamoxifen citrate(Antineoplastic agents