Modulation of the StAR protein and P450scc expressions in previtellogenic salmon oocytes by PCB congener 77 | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

2184688

Reference Type

Journal Article

Title

Modulation of the StAR protein and P450scc expressions in previtellogenic salmon oocytes by PCB congener 77

Author(s)

Sodahl, JA; Arukwe, A

Year

2008

Is Peer Reviewed?

Yes

Journal

Cybium
ISSN: 0399-0974

Volume

Issue

Page Numbers

258-259

Web of Science Id

WOS:000267276400130

Abstract

Previtellogenic oocytes from Atlantic salmon were exposed to different concentrations of PCB77 using an in vitro agarose culture system for 3, 7 and 14 days. Overall, our results show time- and concentration-specific effects of PCB77 on key steroidogenic enzyme, P450scc and protein, StAR at the mRNA level, as well as protein level using immunohistochemical analysis.

Keywords

Previtellogenic oocytes; PCB77; Atlantic salmon; Q-PCR; Histology