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HERO ID
3009719
Reference Type
Journal Article
Title
Short-term exposure to ambient air pollution and coronary heart disease mortality in 8 Chinese cities
Author(s)
Li, H; Chen, R; Meng, X; Zhao, Z; Cai, J; Wang, C; Yang, C; Kan, H
Year
2015
Is Peer Reviewed?
Yes
Journal
International Journal of Cardiology
ISSN:
0167-5273
EISSN:
1874-1754
Volume
197
Page Numbers
265-270
Language
English
PMID
26142971
DOI
10.1016/j.ijcard.2015.06.050
Web of Science Id
WOS:000360319700061
Relationship(s)
is supplemented by
3103153
Supplemental data:
Abstract
BACKGROUND:
Coronary heart disease (CHD) accounted for a large fraction of death globally. The association between air pollution and CHD has been reported, but evidence from highly-polluted regions was scarce. We aimed to estimate the acute effects of outdoor air pollution on daily CHD mortality in China.
METHODS:
We collected daily CHD deaths in 8 large Chinese cities from 1996 to 2008. We firstly obtained the city-specific effect estimates of air pollution using generalized additive models with quasi-Poisson regression, controlling for time trends, meteorological indicators and day of the week. The random-effect model in meta-analysis was used to pool the exposure-response relationships.
RESULTS:
We identified a total of 0.13 million CHD deaths. On average, an increase of 10μg/m(3) in 2-day moving average concentrations of particulate matter≤10μm in aerodynamic diameter (PM10), sulfur dioxide (SO2) and nitrogen dioxide (NO2) was significantly associated with increases of 0.36% [95% confidence intervals (CIs): 0.12%, 0.61%], 0.86% (95% CIs: 0.30%,1.41%) and 1.30% (95% CIs: 0.45%, 2.14%) in daily CHD mortality over the 8 Chinese cities, respectively. The pooled exposure-response curves were almost linear and no apparent thresholds were identified. The effects were more pronounced in cities with lower levels of air pollution. The effects of PM10 and NO2 were more robust than SO2.
CONCLUSION:
Our findings contributed to the very limited evidence regarding the hazardous effects of ambient air pollution on CHD mortality in highly-polluted regions such as China.
Keywords
Air pollution; Coronary heart disease; Mortality; China; Epidemiology
Tags
•
ISA-PM (2019)
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ST PM Mortality
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LitSearch-NOx (2024)
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