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4785808 
Book/Book Chapter 
Arsenic, cadmium, and lead 
Flora, SJS; Agrawal, S 
2017 
Academic Press 
San Diego, CA 
Reproductive and developmental toxicology 
537-566 
English 
WOS:000463378100031 
has other version or edition 4138885 Arsenic, cadmium and lead
is a chapter of 4779372 Reproductive and developmental toxicology (Second edition)
Heavy metals are ubiquitously found entities that not only damage the vital organs of the body but also play a negative role in causing damage to the reproductive organs of the body. This chapter deals with the occurrence and mechanism of toxicity of arsenic, cadmium, and lead mainly focusing on the male and female reproductive organs and the developing organism. The reproductive toxicity study deals with the target of the metals in the gonads, whereas the developmental toxicity covers the effects of the metals on the fertilized ovum, embryo, fetus, and offspring. This chapter also deals with the molecular mechanism of the toxic manifestations generated by the three metals/metalloids. Chelating therapy plays a major role in the treatment of toxicity caused by acute and chronic metal poisoning. Thus, the chapter also discusses the possible effective treatments such as the role of antioxidants and treatment with an effective chelator against the embryotoxic and teratogenic effects. 
Antioxidants; Chelation therapy; Developmental toxicity; Gestation; Heavy metals; Oxidative stress; Prenatal exposure; Reproductive toxicity; Teratogenicity 
2nd 
Gupta, RC 
9780128042397