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HERO ID
48648
Reference Type
Journal Article
Title
Neutrophil functions in lead-exposed workers
Author(s)
Bergeret, A; Pouget, E; Tedone, R; Meygert, T; Cadot, R; Descotes, J
Year
1990
Is Peer Reviewed?
Yes
Journal
Human & Experimental Toxicology
ISSN:
0960-3271
EISSN:
1477-0903
Volume
9
Issue
4
Page Numbers
231-233
Language
English
PMID
2390320
DOI
10.1177/096032719000900405
Web of Science Id
WOS:A1990DT19000005
Abstract
Neutrophil functions were studied in 38 lead-exposed workers compared to 34 controls. Both groups were matched according to age, sex, drinking and smoking habits, ethnic origin and drug intake. Blood lead levels were found to be seven times higher in exposed workers than in controls. Phagocytosis assayed by chemiluminescence was found to be slightly but not significantly altered in exposed workers. In contrast, chemotaxis using the agarose technique was significantly depressed. These results are in agreement with previous in-vitro findings. A further assessment of clinical consequences is warranted.
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