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Citation
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HERO ID
5018064
Reference Type
Journal Article
Title
Body burden of organohalogenated pollutants and polycyclic aromatic hydrocarbons in Romanian population: Influence of age, gender, body mass index, and habitat
Author(s)
Luzardo, OP; Badea, M; Zumbado, M; Rogozea, L; Floroian, L; Ilea, A; Moga, M; Sechel, G; Boada, LD; Henríquez-Hernández, LA
Year
2019
Is Peer Reviewed?
1
Journal
Science of the Total Environment
ISSN:
0048-9697
EISSN:
1879-1026
Publisher
Elsevier B.V.
Location
AMSTERDAM
Volume
656
Page Numbers
709-716
Language
English
PMID
30530140
DOI
10.1016/j.scitotenv.2018.11.404
Web of Science Id
WOS:000455039600069
URL
http://
://WOS:000455039600069
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Abstract
Persistent organochlorine pollutants (POPs) are highly lipophilic and resistant to degradation, hence these substances are commonly found in the environment even decades after their prohibition. The aim of the present study was to determine human serum concentrations of POPs and polycyclic aromatic hydrocarbons (PAHs) in the Romanian population, investigating the role of demographic variables on the body burden of such chemicals. A cross-sectional study including a total of 121 subjects from Brasov (Transylvania region) was designed. The concentration of 62 chemicals, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (BDEs) and PAHs, was measured by gas chromatography-mass spectrometry (GC-MS) in the serum of the participants. p,p'-DDE and β-HCH were detected in 100% and 62% of the series (median values = 2.1 and 0.5 μg/L); PCB-153 was detected in 77.7% of the subjects and PCB-28 showed the highest median concentration (0.5 μg/L); BDE-47 was detected at a low concentration in 11.6% of the individuals; phenanthrene and naphthalene were present in 98.3% and 38.8% of the serum samples (median values = 0.9 and 6.5 μg/L, respectively). Age was the main determinant of the total body burden of OCPs and PCBs. A positive correlation was observed between p,p'-DDE and age (Spearman Rho = 0.312, P < 0.0001), suggesting the prevalence of higher levels of pollutants at older ages. The present results showed a significant decrease in serum levels of p,p'-DDE and HCH in Romania -a country which has traditionally reported higher values than other Eastern European countries- as well as low levels of PCBs and BDEs. The presence of PAHs suggests an unknown source of exposure that deserves further investigation.
Keywords
Human serum; Organochlorine pesticides; Polybrominated diphenyl ethers; Polychlorinated biphenyls; Polycyclic aromatic hydrocarbons; Romania
Tags
IRIS
•
Naphthalene
Database Searches
PubMed
WOS
Combined data set
Data set for title/abstract screening
Excluded - PECO criteria not met (TIAB)
Feb 2019 Update
PubMed
WOS
•
PCBs
Not prioritized for screening
Litsearches
Litsearch: Aug 2018 - Aug 2019
PubMed
Not prioritized for screening
•
Naphthalene (2021 Evidence mapping publication)
Database Searches
PubMed
WOS
Combined data set
Data set for title/abstract screening
Excluded – PECO criteria not met
Feb 2019 Update
PubMed
WOS
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