Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
99104
Reference Type
Journal Article
Title
Fine particulate matter and mortality: a comparison of the six cities and American Cancer Society cohorts with a medicare cohort
Author(s)
Eftim, SE; Samet, JM; Janes, H; Mcdermott, A; Dominici, F
Year
2008
Is Peer Reviewed?
Yes
Journal
Epidemiology
ISSN:
1044-3983
EISSN:
1531-5487
Volume
19
Issue
2
Page Numbers
209-216
Language
English
PMID
18223484
DOI
10.1097/EDE.0b013e3181632c09
Web of Science Id
WOS:000253401400009
Abstract
BACKGROUND: The American Cancer Society study and the Harvard Six Cities study are 2 landmark cohort studies for estimating the chronic effects of fine particulate air pollution (PM2.5) on mortality. Using Medicare data, we assessed the association of PM2.5 with mortality for the same locations included in these studies. METHODS: We estimated the chronic effects of PM2.5 on mortality for the period 2000-2002 using mortality data for cohorts of Medicare participants and average PM2.5 levels from monitors in the same counties included in the 2 studies. We estimated mortality risk associated with air pollution adjusting for individual-level (age and sex) and area-level covariates (education, income level, poverty, and employment). We controlled for potential confounding by cigarette smoking by including standardized mortality ratios for lung cancer and chronic obstructive pulmonary disease. RESULTS: Using the Medicare data, we estimated that a 10 microg/m increase in the yearly average PM2.5 concentration is associated with 10.9% (95% confidence interval = 9.0-12.8) and with 20.8% (14.8-27.1) increases in all-cause mortality for the American Cancer Society and Harvard Six Cities study counties, respectively. The estimates are somewhat higher than those reported by the original investigators. CONCLUSION: Although Medicare data lack information on some potential confounding factors, we estimated risks similar to those in the previously published reports, which incorporated more extensive information on individual-level confounders. We propose that the Medicare files can be used to construct on-going cohorts for tracking the risk of air pollution over time.
Tags
NAAQS
•
ISA-NOx (2016)
•
ISA-PM (2009 Final Project Page)
2009 Final
•
ISA-PM (2019)
Final ISA
Chapter 11
•
Litsearch – PM ISA Supplement 2021
Pubmed iCite citation search (April 2021 BR)
PM2.5 Cardiovascular and Mortality Epi Search
2019 PM ISA Seed
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity