This profile on naphthalene (91203), 1-methylnaphthalene (90120), and 2-methylnaphthalene (91576) summarized toxicologic and adverse health effects information. The profile contained a public health statement which considered what happens to any of these compounds once it enter the environment, how an individual might be exposed, how the chemicals enter and leave the body, what effect they can have on health, whether there is a medical test to determine if exposure has occurred, federal recommendations pertaining to protecting individuals, and sources of additional information. Health effects were considered for exposure via inhalation, oral or dermal routes. Each exposure route discussed the potential for effects including death, systemic effects, immunological and lymphoreticular effects, neurological effects, reproductive effects, developmental effects, genotoxic effects, and cancer. Other topics covered include biomarkers of exposure and effect, interaction with other substances, populations that are unusually susceptible, methods for reducing toxic effects, and the adequacy of the database. Chemical and physical information was discussed, along with production, import/export, use and disposal of the chemical. The potential for human exposure, analytical methods, regulations and advisories for naphthalene were considered. Naphthalene has been used in chemical production, resin production, the dyeing industry, pharmaceutical manufacturing, insect repellents manufacturing, leather tanning materials and paper coating formulations. 1-Methylnaphthalene and 2-methylnaphthalene have been used in the production of chemicals. All three compounds may be found in cigarette and wood smoke, and at some hazardous waste sites.
NAPHTHALENE; 1-METHYLNAPHTHALENE; 2-METHYLNAPHTHALENE; TOXICOLOGY; TOXICITY EVALUATION; HEALTH HAZARDS; USA; CRITERIA DOCUMENT; TOXIC EFFECTS; LITERATURE SURVEY; EXPOSURE EVALUATION; LIMITATION OF EXPOSURE; GLOSSARY; BLOOD-CELL ANOMALIES; HAEMOLYTIC ANAEMIA; EMBRYOTOXIC EFFECTS; CATARACTOGENIC EFFECTS; IRRITATION; LUNG DISEASES; JAUNDICE; GASTROINTESTINAL DISEASES; ILO
