Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
1508720
Reference Type
Journal Article
Title
Detection of human papillomavirus genotypes associated with mucopurulent cervicitis and cervical cancer in Changchun, China
Author(s)
Liu, W; Wu, EQ; Yu, XH; Feng, LH; Jiang, CL; Zha, X; Kong, W
Year
2013
Is Peer Reviewed?
Yes
Journal
International Journal of Gynecology and Obstetrics
ISSN:
0020-7292
EISSN:
1879-3479
Volume
120
Issue
2
Page Numbers
124-126
Language
English
PMID
23245674
DOI
10.1016/j.ijgo.2012.07.032
Web of Science Id
WOS:000314433400004
Abstract
OBJECTIVE:
To determine the prevalence and genotype distribution of human papillomavirus (HPV) infection among Chinese patients with mucopurulent cervicitis (MPC) or cervical cancer (CC).
METHODS:
In total, 191 cases of CC (n=66), acute MPC (n=84), and healthy cervix controls (n=41) were initially included; samples were collected between May 21, 2008, and October 9, 2011. Cervical specimens were screened for HPV using a nested polymerase chain reaction assay and DNA sequencing.
RESULTS:
Overall prevalence of HPV infection was 20.0% in the control group, 53.3% in the MPC group, and 93.8% in the CC group. The predominant genotype detected in all 3 groups was the oncogenic variant HPV 16 (87.7%, 18.7%, and 10.0% in the CC, MPC and control specimens, respectively). The second most frequent genotype among patients with MPC was HPV 58. This variant is also oncogenic and was detected at a higher rate in the MPC group (9.3%) than in the control (2.5%) and CC (1.5%) groups.
CONCLUSION:
Infection with HPV was prevalent among Chinese women with MPC or CC. Furthermore, the high prevalence of oncogenic genotypes observed among HPV-positive patients with MPC suggests that this group is at increased risk of developing CC.
Tags
IRIS
•
Arsenic Hazard ID
PubMed
Considered New
2. Lit Search Updates through Oct 2015
PubMed
Considered
7. Other Studies through Oct 2015
Non-Arsenic
•
Arsenic (Inorganic)
1. Literature
Lit search updates through Oct 2015
3. Hazard ID Screening
Other potentially supporting studies
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity