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1598301 
Journal Article 
Degradation of tissue conditioners in complete dentures: an in situ study 
Elsemann, RB; Cosme, DC; Souto, AA; da Silva, DF; de Mello, JS; Shinkai, RS 
2008 
Yes 
International Journal of Prosthodontics
ISSN: 0893-2174 
21 
6 
486-488 
English 
19149062 
This in situ study evaluated the Shore A hardness and phthalate concentration of 3 tissue conditioners (Coe-Comfort, Dura Conditioner, Softone) inserted into grooves on 9 maxillary dentures. Data were collected at baseline and after 3, 7, and 14 days of denture use. All materials showed a decrease in phthalate concentration and an increase in hardness over time, but the largest changes occurred during the first 3 days; 59% to 74% of the hardness variability was explained by the phthalate concentration. Overall, Coe-Comfort was softer and had less alteration in its phthalate concentration than Dura Conditioner and Softone up to day 7.