Effects of xenobiotics on ion transport and its adrenergic regulation in erythrocyte membranes of Abramis brama and Cyprinus carpio | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1784518

Reference Type

Journal Article

Title

Effects of xenobiotics on ion transport and its adrenergic regulation in erythrocyte membranes of Abramis brama and Cyprinus carpio

Author(s)

Nagdaliev, FF; Kotelevtsev, SV; Kozlovskaya, VI; German, AV

Year

1995

Is Peer Reviewed?

Journal

Voprosy Ikhtiologii
ISSN: 0042-8752

Report Number

BIOSIS/96/05681

Volume

Issue

Page Numbers

394-401

Language

Russian

Abstract

BIOSIS COPYRIGHT: BIOL ABS. Pollution of Rybinsk Reservoir area adjacent to the city of Cherepovets (Russia) leads to an increase in the passive permeability of erythrocyte membrane in Abramis brama and in the activity of Na+, K+-pump. Depending of the dose, sovol, a polychlorinated biphenyl mixture injected in Abramis brama and Cyprinus carpio increases or decreases activity rate of Na+,K+pump, lowers membrane passive permeability for rubidium-86, and modifies hormonal regulation of co-transport. Sovol inhibited norepinephrine-induced activation of Na+, K+-pump by many times in all the experiments. Exposing carp erythrocytes to a medium with 20-methylcholanthrene increased passive membrane permeability and lowered the activity of Na+, K+-pump. Sovol also inhibits the activity of Na+, K+-pump, but it does not decrease passive membrane permeability.

Keywords

Cytology and Cytochemistry-Animal; Biochemical Studies-General; Biophysics-General Biophysical Studies; Blood; Endocrine System-General; Toxicology-Environmental and Industrial Toxicology; Public Health: Environmental Health-Air; Osteichthyes