US EPA

2160849 

Journal Article 

Recent advances in mass spectrometric measurement of dioxins 

Focant, JF; Pirard, C; Eppe, G; De Pauw, E 

2005 

Yes 

Journal of Chromatography A
ISSN: 0021-9673
EISSN: 1873-3778 

ELSEVIER 

AMSTERDAM 

1067 

1-2 

265-275 

English 

15844532 

10.1016/j.chroma.2004.10.095 

WOS:000227925800025 

Past years, many efforts have been dedicated to the development of alternative analytical methods for the measurement of dioxins in various types of matrices. Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are compounds that are present in samples at part-per-billion (ppb) or part-per-trillion (ppt) level. Their measurement requires the use of very sensitive analytical methods. Gas chromatography (GC) coupled to quadrupole ion storage mass spectrometry (QISTMS), fast GC (FGC) coupled to time-of-flight mass spectrometry (TOFMS) and comprehensive two-dimensional gas chromatography (GC x GC) coupled to TOFMS are the more promising tools challenging the reference GC high resolution mass spectrometry (HRMS) based on sector instruments. We report herein some of the advances we achieved in the past years in our laboratory on the development of alternative measurement methods for those compounds. 

quadrupole ion storage mass spectrometry; tandem in time mass spectrometry; time-of-flight mass spectrometry; polychlorinated dibenzo-p-dioxins; polychlorinated dibenzofurans; polychlorinated biphenyls