Induction of hepatic microsomal-enzymes by Aroclor 1254 in Ictalurus-punctatus (channel catfish) | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

2166328

Reference Type

Journal Article

Title

Induction of hepatic microsomal-enzymes by Aroclor 1254 in Ictalurus-punctatus (channel catfish)

Author(s)

Hill, DW; Hejtmancik, E; Camp, BJ

Year

1976

Is Peer Reviewed?

Yes

Journal

Bulletin of Environmental Contamination and Toxicology
ISSN: 0007-4861
EISSN: 1432-0800

Volume

Issue

Page Numbers

495-502

Language

English

DOI

10.1007/BF01686169

Web of Science Id

WOS:A1976CN37300021

URL

https://www.proquest.com/scholarly-journals/induction-hepatic-microsomal-enzymes-aroclor-1254/docview/14088531/se-2?accountid=171501
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Abstract

The effects of Aroclor 1254 on hepatic microsomal enzyme activity and mitochondrial respiration, and the interaction of the PCB's exposure and retention time in channel catfish are determined. Data indicate that at a 2 ppm dose level, a maximum concentration of PCB's is obtained in all tissues after 12 hr exposure and is maintained for at least 480 hr post-exposure. Exposure significantly increases both animopyrine N-demethylase and aniline hydroxylase activities. Aroclor 1254 at moderate concentrations does not affect electron transport or oxidative phosphorylation in liver mitochondria.

Keywords

Environment Abstracts; AROCLOR; CATFISH; PATHOLOGY, FISHLABORATORY; CHEMICAL CONTAMINATION; ENA 07:General