US EPA

2533386 

Journal Article 

Comparing human exposure to emerging and legacy flame retardants from the indoor environment and diet with concentrations measured in serum 

Cequier, E; Marcé, RM; Becher, G; Thomsen, C 

2015 

1 

Environment International
ISSN: 0160-4120
EISSN: 1873-6750 

Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom 

74 

54-59 

English 

25454220 

10.1016/j.envint.2014.10.003 

WOS:000346681700007 

This study investigates associations between serum concentrations of emerging and legacy halogenated flame retardants (HFRs) in 46 Norwegian women and measured indoor air and dust concentrations of the HFRs as well as detailed information on diet and household factors. Hexabromobenzene (median 0.03ng/g lipid) and Dechlorane 602 (median 0.18ng/g lipid) were detected in about 50% of the samples and Dechlorane Plus syn (median 0.45ng/g lipid) and anti (median 0.85ng/g lipid) in more than 78%. The most abundant polybrominated diphenyl ethers were 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE-153; median 0.82ng/g lipid) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47; median 0.49ng/g lipid) detected in more than 70% of the samples. In the bivariate analysis, no consistent associations were observed between the biomonitoring data and measured concentrations in indoor air and dust. On the other hand, consumption of specific food items (mainly lamb/mutton and margarine) correlated significantly with more than two HFR serum concentrations, while this was not the case for household factors (electronic appliances). Only the significant bivariate associations with diet were confirmed by multivariate linear regression analyses, which might indicate a higher contribution from food compared to the indoor environment to the variation of the body burden of these HFRs. 

Dietary exposure; Emerging flame retardant; Indoor; Polybrominated diphenyl ether; Blood; Dust