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Citation
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HERO ID
3223108
Reference Type
Journal Article
Title
Typical halogenated persistent organic pollutants in indoor dust and the associations with childhood asthma in Shanghai, China
Author(s)
Meng, G; Nie, Z; Feng, Y; Wu, X; Yin, Y; Wang, Y
Year
2016
Is Peer Reviewed?
Yes
Journal
Environmental Pollution
ISSN:
0269-7491
EISSN:
1873-6424
Volume
211
Page Numbers
389-398
Language
English
PMID
26798999
DOI
10.1016/j.envpol.2015.12.006
Web of Science Id
WOS:000376696800044
URL
https://search.proquest.com/docview/1773232593?accountid=171501
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Abstract
Halogenated persistent organic pollutants (Hal-POPs) are significant contaminants in the indoor environment that are related to many human diseases. Ingestion of indoor dust is considered the major pathway of Hal-POP exposures, especially for children aged 3-6 years. Alongside a retrospective study on the associations between typical Hal-POP exposure and childhood asthma in Shanghai, indoor dust samples from asthmatic and non-asthmatic children's homes (n = 60, each) were collected. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) were measured by GC-MS. BDE-209, PCB-8 and p,p'-DDE were the predominant components in each chemical category. The concentrations of most Hal-POPs were significantly higher in the asthmatic families. The associations between Hal-POP exposure and asthma occurrence were examined by calculating the odds ratios (ORs) using a logistic regression model. A positive association was found between p,p'-DDE in indoor dust and childhood asthma (OR = 1.825, 95%CI: 1.004, 3.317; p = 0.048). The average daily doses of Hal-POP intake were calculated using the method provided by the USEPA. Non-carcinogenic health risks were preliminarily assessed. Our study indicated that exposure to p,p'-DDE via indoor dust may contribute to childhood asthma occurrence. Non-carcinogenic health risks were not found with the intake of Hal-POPs via the ingestion of indoor dust.
Keywords
Halogenated persistent organic pollutants; Childhood asthma; Indoor dust; Exposure assessment; Positive association
Tags
IRIS
•
PCBs
Hazard ID: Epidemiological evidence
Litsearches
Litsearch Aug 2015 - Aug 2016
Pubmed
•
PCBs Epi Hazard ID
Health Effects
Immunological
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