Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3224029
Reference Type
Journal Article
Title
Different effects of long-term exposures to SO2 and NO2 air pollutants on asthma severity in young adults
Author(s)
Greenberg, N; Carel, RS; Derazne, E; Bibi, H; Shpriz, M; Tzur, D; Portnov, BA
Year
2016
Is Peer Reviewed?
1
Journal
Journal of Toxicology and Environmental Health, Part A: Current Issues
ISSN:
1528-7394
EISSN:
1087-2620
Volume
79
Issue
8
Page Numbers
1-10
Language
English
PMID
27092440
DOI
10.1080/15287394.2016.1153548
Web of Science Id
WOS:000378118000002
Abstract
Numerous studies demonstrated that exposure to ambient air pollutants contributes to severity and frequency of asthma exacerbations. However, whether common air pollutants, such as nitrogen dioxide (NO2) and sulfur dioxide (SO2), exert differential effects on asthma occurrence and severity is unclear. The aim of this investigation was to determine whether exposure to NO2 and/or SO2 may initiate different long-term effects on prevalence and severity of asthma in young adults. Medical records of 137,040 males, 17 years old, who underwent standard premilitary service health examinations during 1999-2008 were examined. Air-pollution data for NO2 and SO2 were linked to the place of residence of each subject. The influence of specific air pollutants on asthma prevalence and severity was evaluated using bivariate logistic regression, controlling for individuals' sociodemographic attributes. For both ambient air pollutants, there was a significant dose-response effect on severity of asthma at ambient concentrations below the current National Ambient Air Quality Standards. However, in residential areas with high levels of SO2 (13.3-592.7µg/m(3)) and high levels of NO2 (27.2-43.2µg/m(3)) the risk of asthma occurrence was significantly higher than that in residential areas with high levels of NO2 (27.2-43.2 µg/m(3)) and intermediate levels (6.7-13.3 µg/m(3)) of SO2 pollution. The effects of exposure to SO2 and NO2 air pollutants on the respiratory airways system appear to differ, with possible implications regarding medical management, even in cases of exposure to mixtures of these pollutants.
Tags
•
ISA-PM (2019)
•
ISA-SOx
Health Effects
Considered
Cited Second ERD Dec2016
Cited in Final ISA Dec2017
Chapter 5 – Health
•
LitSearch-NOx (2024)
Forward Citation Search
Epidemiology
Results
Cardiovascular-ST
PubMed
WoS
Cardiovascular-LT
PubMed
WoS
Respiratory-LT
PubMed
WoS
Respiratory-ST
PubMed
WoS
Exposure
Results
Confounding
PubMed
WoS
Keyword Search
Epidemiology
Respiratory
PubMed
WoS
March 2014-November 2016
Exposure
Confounding
WoS
PIA
WoS
PubMed
Toxicology
March 2014-November 2016
Dosimetry
General Strategy
PubMed
WoS
TIAB Screening
Epidemiology
Include
Respiratory
Cardiovascular
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity