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HERO ID
510169
Reference Type
Journal Article
Title
A case of neuropathy mimicking Guillain-Barre syndrome after arsenic intoxication
Author(s)
Perriol, MP; Devos, D; Hurtevent, JF; Tiffreau, V; Saulnier, F; Destee, A; Defebvre, L
Year
2006
Is Peer Reviewed?
1
Journal
Revue Neurologique
ISSN:
0035-3787
Volume
162
Issue
3
Page Numbers
374-377
Language
French
PMID
16585894
DOI
10.1016/s0035-3787(06)75025-1
Web of Science Id
WOS:000236852400013
Abstract
Introduction. Chronic arsenic toxicity is a global health problem affecting millions of people. Acute arsenic poisoning is less frequent and it is most often lethal. Therefore, its consequences are not well known, more precisely its neurological consequences. Observation. We report a case of Guillain-Barre-like syndrome and encephalopathy after acute arsenical poisoning in a 50 year-old man. After 4 month follow-up, the improvement was slow and limited with persistent motor and proprioceptive deficits. Discussion. The most frequent neurological complication induced by acute arsenical poisoning is a distal, symmetrical, sensory, axonal polyneuropathy. Yet the clinical course and the electrophysiological findings may also suggest a Guillain-Barre like syndrome. Moreover, the chelating is not very effective on the neurological complications. Conclusion. Any discrepancies in the clinical course of a Guillain-Barre syndrome shall lead to reconsider the diagnosis. The association of gastro-intestinal disorders, skin lesions, and encephalopathy and mood disorders leads to discuss intoxication with heavy metal and more precisely with arsenic. Moreover, the chelating is not very effective on the neurological complications.
Keywords
Guillain-Barre; neuropathy; acute arsenic intoxication
Tags
IRIS
•
Arsenic (Inorganic)
1. Literature
PubMed
Toxline, TSCATS, & DART
Web of Science
2. Initial Filter
Non peer-reviewed
Non English
•
Inorganic Arsenic (7440-38-2) [Final 2025]
1. Initial Lit Search
PubMed
WOS
ToxNet
3. Initial Filter through Oct 2015
Non-English
Non Peer-Reviewed
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