A review of possible toxicity of di-2-ethylhexylphthalate (DEHP) in plastic intravenous containers: Effects on reproduction | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

681977

Reference Type

Journal Article

Subtype

Review

Title

A review of possible toxicity of di-2-ethylhexylphthalate (DEHP) in plastic intravenous containers: Effects on reproduction

Author(s)

Kaul, AF; Souney, PF; Osathanondh, R

Year

1982

Is Peer Reviewed?

Yes

Journal

Drug Intelligence in Clinical Pharmacy
ISSN: 0012-6578

Volume

Issue

Page Numbers

689-692

Language

English

PMID

6751754

DOI

10.1177/106002808201600908

Web of Science Id

WOS:A1982PF48500007

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019972316&doi=10.1177%2f106002808201600908&partnerID=40&md5=436deac7213efcc9cf2e1f8ecab616b3
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Abstract

Many containers for intravenous solutions are made with plasticized polyvinyl chloride, the common form of which is di-2-ethylhexylphthalate (DEHP). Extraction of DEHP into blood and plasma stored in such plastic containers can occur, and harmful effects of DEHP in the human body consequently have been suggested. Reports on toxicity of DEHP in animals during pregnancy and the developmental period are critically reviewed.

Keywords

adverse effects; Animals; Biotransformation; blood; Diethylhexyl Phthalate; drug effects; Female; Humans; Injections,Intravenous; metabolism; Phthalic Acids; Plasma; Polyvinyl Chloride; Pregnancy; Reproduction; Solutions; toxicity