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1255524 
Journal Article 
Bioremediation and human tolerance to heavy metals through microbial processes: A potential role for probiotics? 
Monachese, M; Burton, JP; Reid, G 
In Press 
Yes 
Applied and Environmental Microbiology
ISSN: 0099-2240
EISSN: 1098-5336 
78 
18 
6397-6404 
English 
The food and water we consume are often contaminated with a range of chemicals and heavy metals such as lead, cadmium, arsenic, chromium and mercury that are able to cause debilitating health complications. Though heavy metal exposure and contamination are not a recent phenomenon, the concentration of metals and exposure to populations remains a major issue despite remediation interventions. The ability to prevent and manage this problem is still a subject of much debate with many ineffective technologies and others too expensive for practical large- scale use, especially for developing nations where major pollution occurs. This has led researchers to seek alternative solutions for decontaminating environmental sites and humans themselves. A number of environmental microorganisms have long been known for their ability to bind metals, but less well appreciated are human gastrointestinal bacteria. Species such as Lactobacillus present in the human mouth, gut and vagina and in fermented foods, have the ability to bind and detoxify some of these substances. This review examined the current understanding of detoxication mechanisms of lactobacilli and how in the future humans and animals might benefit from these organisms in remediating environmental contamination of food. 
IRIS
• Arsenic Hazard ID
     1. Initial Lit Search
          PubMed
          WOS
          ToxNet
          WOS
          Considered New
     2. Lit Search Updates through Oct 2015
          WOS
          Considered
     4. Considered through Oct 2015
     6. Cluster Filter through Oct 2015
     7. Other Studies through Oct 2015
          Other
• Arsenic (Inorganic)
     1. Literature
          PubMed
          Toxline, TSCATS, & DART
          Web of Science
          Lit search updates through Oct 2015
     3. Hazard ID Screening
          Other potentially supporting studies
     5. Susceptibility Screening
          Excluded/Not relevant
• Arsenic Susceptibility
     4. Susceptibility and Lifestages
          Microbiome
     5. Health Effect
          Not Relevant
     1. Susceptibility Literature Screening
          Keyword Search
     2. Excluded
          Not Relevant
     3. References Identified During Review
• Methylmercury
     ADME Search: Jan 1990 - Nov 2018
          Results with mercury
               PubMed
               WoS