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202651 
Journal Article 
The fetotoxicity of a polychlorinated biphenyl mixture (Aroclor 1254) in the rabbit and in the rat 
Villeneuve, DC; Grant, DL; Khera, K; Clegg, DJ; Baer, H; Phillips, WEJ 
1971 
0 
Environmental Physiology
ISSN: 0142-8659 
NIOSH/00080403 
1 
67-71 
Aroclor® 1254 was not associated with fetotoxic effects in rabbits which received orally 1 or 10 mg/kg daily for the first 28 days of gestation or in rats which were dosed orally with 6.25 - 100 mg/kg/day from the 6th to 15th day of gestation. Doses of 12.5 to 50 mg/kg/day did induce abortions and were fetopathic to rabbits when treated for the first 28 days of gestation. The results indicated that the rabbit fetus was more sensitive to toxic effects of Aroclor® 1254 than the rat fetus. 
IRIS
• PCBs
     Hazard ID: Toxicological evidence
     Litsearches
               ToxLine
          Initial Filter
               Non Peer-Reviewed
          LitSearch August 2015
               Toxline
     Cited (Nov 2012)
     Seed References
• PCBs Tox Hazard ID
     Health Effects
          Cardiovascular
          Developmental
          Hepatic
          Immunological
          Neurological
          Renal