US EPA

2177855 

Journal Article 

Effects of p,p'-DDT, p,p'-DDD, and p,p'-DDE on oxygen uptake in the freshwater planarian (Phagocata gracilis) 

Batey, BH; Wells, MR 

1980 

Yes 

Bulletin of Environmental Contamination and Toxicology
ISSN: 0007-4861
EISSN: 1432-0800 

PESTAB/80/0768 

24 

1 

128-133 

English 

7357102 

WOS:A1980HY13500021 

https://search.proquest.com/docview/75036049?accountid=171501
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PESTAB. To determine the toxic effects of DDT and its degradation products, starved planarians (Phagocata gracilis) were given beef liver perfused with corn oil containing 10 ppm p,p'-DDT, p,p'-DDE, or p,p'-DDD (TDE). No symptoms of DDT poisoning or DDT-related mortality were noted in the organisms exposed to these substances for 60 min periods. Oxygen uptake was significantly increased in the planarians fed beef liver alone. There were no significant differences over a 96 hr period between the oxygen uptake in planarians fed beef liver perfused with DDT, DDE, or DDD in corn oil an planarians fed beef liver perfused with corn oil alone. Possible reasons for the absence of a toxic effect of DDT to planarians, including the presence of a detoxifying microsomal enzyme system and the non-accumulation of DDT in the organisms, are reviewed. 

Proteins; Dichlorodiphenyl Dichloroethylene; 4M7FS82U08; CIW5S16655; Dichlorodiphenyldichloroethane; V14159DF29; Index Medicus; Liver -- metabolism; Animals; Time Factors; Proteins -- metabolism; Dichlorodiphenyldichloroethane -- toxicity; Planarians -- metabolism; Planarians -- drug effects; Turbellaria -- metabolism; Dichlorodiphenyl Dichloroethylene -- toxicity; DDT -- toxicity; Oxygen Consumption -- drug effects