US EPA

2178241 

Journal Article 

Further studies on the toxicity of DDT to Planaria 

Kouyoumjian, HH; Villeneuve, JP 

1979 

Yes 

Bulletin of Environmental Contamination and Toxicology
ISSN: 0007-4861
EISSN: 1432-0800 

PESTAB/80/0414 

22 

1-2 

108-112 

English 

465768 

https://search.proquest.com/docview/74651250?accountid=171501
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PESTAB. Colonies of P. felina and C. alpina were placed in p,p'-DDT. Test animals were removed from the experimental dishes at 0.25, 0.5, 1, 2, 3, 4, 7, and 14 days. Initial GLC analyses of planaria demonstrated relatively low levels of organochlorine pesticide residues 0 mug/g for DDT, 0.02 mug/g for DDD (TDE) and 0.05 mug/g for DDE. During the first 24 hours of exposure at 0.15 ppm levels, decapitated planaria were able to resist DDT absorption with subsequent low levels of DDD and DDE. After 24 hours, however, regenerating planaria absorbed DDT at an increased rate. The DDT thus absorbed slowed down the rate of regeneration. DDE appeared to be the major metabolite. Inhibitory effects of DDT were noted on asexual fission and on eye regeneration. 

Dichlorodiphenyl Dichloroethylene; 4M7FS82U08; CIW5S16655; Dichlorodiphenyldichloroethane; V14159DF29; Index Medicus; Animals; Regeneration -- drug effects; Time Factors; Dichlorodiphenyldichloroethane -- metabolism; Dichlorodiphenyl Dichloroethylene -- metabolism; Reproduction, Asexual -- drug effects; DDT -- pharmacology; Planarians -- metabolism; Planarians -- drug effects; Turbellaria -- drug effects; DDT -- metabolism