US EPA

3045651 

Journal Article 

Elucidating the Links Between Endocrine Disruptors and Neurodevelopment 

Schug, TT; Blawas, AM; Gray, K; Heindel, JJ; Lawler, CP 

2015 

Yes 

Endocrinology
ISSN: 0013-7227
EISSN: 1945-7170 

156 

6 

1941-1951 

English 

25714811 

10.1210/en.2014-1734 

WOS:000358435400004 

http://dx.doi.org/10.1210/en.2014-1734
Exit
 

Recent data indicate that approximately 12% of children in the United States are affected by neurodevelopmental disorders, including attention deficit hyperactivity disorder, learning disorders, intellectual disabilities, and autism spectrum disorders. Accumulating evidence indicates a multifactorial etiology for these disorders, with social, physical, genetic susceptibility, nutritional factors, and chemical toxicants acting together to influence risk. Exposure to endocrine-disrupting chemicals during the early stages of life can disrupt normal patterns of development and thus alter brain function and disease susceptibility later in life. This article highlights research efforts and pinpoints approaches that could shed light on the possible associations between environmental chemicals that act on the endocrine system and compromised neurodevelopmental outcomes.