Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3860738
Reference Type
Journal Article
Title
Orthogonal zirconium diol/C18 liquid chromatography-tandem mass spectrometry analysis of poly and perfluoroalkyl substances in landfill leachate
Author(s)
Allred, BM; Lang, JR; Barlaz, MA; Field, JA
Year
2014
Is Peer Reviewed?
Yes
Journal
Journal of Chromatography A
ISSN:
0021-9673
EISSN:
1873-3778
Publisher
ELSEVIER
Location
AMSTERDAM
Volume
1359
Page Numbers
202-211
Language
English
PMID
25103279
DOI
10.1016/j.chroma.2014.07.056
Web of Science Id
WOS:000340984400025
URL
http://www.sciencedirect.com/science/article/pii/S0021967314011492
Exit
Abstract
Leachates coming from landfills contain a myriad of compounds of potential environmental and human health concern, including per- and polyfluorinated alkyl substances (PFASs). Micro liquid-liquid extraction was combined with a 900μl large volume injection (LVI) for the analysis of 70 PFASs in landfill leachate by orthogonal LC-MS/MS. The LVI approach introduced 7 times more extract than conventional injection approaches. Two zirconium-modified diol guard columns effectively retained PFASs from the organic leachate extract and an analytical C18 column was used for separation. Method accuracy and precision for PFASs with analytical grade reference materials ranged from 81-120% and 5.5-33%, respectively. Estimated method detection limits in the low to sub-ng/L. Seven landfill leachates were analyzed by the optimized analytical method for the purposes of method demonstration. Leachates were characterized by a wide variety of PFASs, reporting on 36 previously-unanalyzed PFASs in leachate. Perfluoroalkyl carboxylates were the most abundant class detected while phosphorous-containing PFASs, present in all leachates, were at low concentrations. The 3-perfluoropentyl propanoate (5:3 FTCA) was the most concentrated analyte in most samples and constitutes a previously unreported but significant component of landfill leachate.
Keywords
Landfill leachates; LVI; LC-MS/MS; PFAS
Tags
PFAS
•
5:3 acid
Literature Search
Pubmed
WOS
Screening Results
Excluded/Not on Topic
•
Additional PFAS (formerly XAgency)
•
^Per- and Polyfluoroalkyl Substances (PFAS)
5:3 acid (914637-49-3)
Literature Search
Pubmed
WOS
•
PFAS 150
Literature Search Update December 2020
WOS
Literature Search August 2019
Web of Science
2H,2H,3H,3H-Perfluorooctanoic acid
Perfluorooctanoic acid
•
PFHxS
•
PFOA (335-67-1) and PFOS (1763-23-1)
Literature Search Update (2013-2019)
WOS
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity